S961 TFA (1083433-49-1 free base) ( —— )

产品货号. M30060 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

S961 TFA (1083433-49-1 free base)
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

S961 TFA is A high affinity insulin receptor (IR) antagonist with IC50 for hir-a, hir-b and human insulin-like growth factor I receptor (higf-ir) at 0.048, 0.027 and 630 nM, respectively.
产品描述

S961 TFA is A high affinity insulin receptor (IR) antagonist with IC50 for hir-a, hir-b and human insulin-like growth factor I receptor (higf-ir) at 0.048, 0.027 and 630 nM, respectively.(In Vitro):S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively.
同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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CAS Number

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分子量

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分子式

C211H297N55O71S2.xC2HF3O2
纯度

>98% (HPLC)
溶解度

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SMILES

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化学全称

Sequence:{Gly}{Ser}{Leu}{Asp}{Glu}{Ser}{Phe}{Tyr}{Asp}{Trp}{Phe}{Glu}{Arg}{Gln}{Leu}{Gly}{Gly}{Gly}{Ser}{Gly}{Gly}{Ser}{Ser}{Leu}{Glu}{Glu}{Glu}{Trp}{Ala}{Gln}{Ile}{Gln}{Cys}{Glu}{Val}{Trp}{Gly}{Arg}{Gly}{Cys}{Pro}{Ser}{Tyr} (Disulfide bridge: Cys33-Cys40)

Sch?ffer L, et al. A novel high-affinity peptide antagonist to the insulin receptor. Biochem Biophys Res Commun. 2008 Nov 14;376(2):380-3.

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